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Chemical structure of RK-20448

GC40547

RK-20448

Also known as 7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine

RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2 (IC50s = 0·24, 1·19, 10·74, and 5·85 μM, respectively)

ChemicalCAS479501-40-1MW482.6FormulaC29H34N6O
CAS number
479501-40-1
Molecular weight
482.6
Formula
C29H34N6O
Solubility
DMSO： 10 mM
InChIKey
FDVSOQRNTAPCHB-UHFFFAOYSA-N
Catalogue number
GC40547
Brand
GLPBIO
Computed properties PubChem CID 6539952 · XLogP 4.5 · TPSA 72.4 Ų · H-bond donors 1
XLogP
4.5
TPSA
72.4 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
36

SMILES CN1CCN(CC1)C2CCC(CC2)N3C=C(C4=C(N=CN=C43)N)C5=CC=C(C=C5)OC6=CC=CC=C6

Computed descriptors from PubChem (CID 6539952), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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