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Chemical structure of RK-287107

GC19505

RK-287107

Also known as 2-[4,6-difluoro-1-(2-hydroxyethyl)spiro[2H-indole-3,4'-piperidine]-1'-yl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one

RK-287107 is a potent and specific tankyrase inhibitor with IC50s of 14·3 and 10·6 nM for tankyrase-1 and tankyrase-2, respectively

ChemicalCAS2171386-10-8MW416.46FormulaC₂₂H₂₆F₂N₄O₂
CAS number
2171386-10-8
Molecular weight
416.46
Formula
C₂₂H₂₆F₂N₄O₂
Solubility
Soluble in DMSO
InChIKey
FZQYCOUBRJEYBC-UHFFFAOYSA-N
Catalogue number
GC19505
Brand
GLPBIO
Computed properties PubChem CID 137701512 · XLogP 2.2 · TPSA 68.2 Ų · H-bond donors 2
XLogP
2.2
TPSA
68.2 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
30

SMILES C1CCC2=C(C1)C(=O)NC(=N2)N3CCC4(CC3)CN(C5=C4C(=CC(=C5)F)F)CCO

Computed descriptors from PubChem (CID 137701512), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.