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Chemical structure of RK-24466 (KIN 001-51)

GC31701

RK-24466 (KIN 001-51)

Also known as 7-cyclopentyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine

RK-24466 (KIN 001-51) (KIN 001-51) is a potent and selective Lck inhibitor; inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively

ChemicalCAS213743-31-8MW370.45FormulaC23H22N4O
CAS number
213743-31-8
Molecular weight
370.45
Formula
C23H22N4O
Solubility
DMSO ： 45 mg/mL (121·47 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
FMETVQKSDIOGPX-UHFFFAOYSA-N
Catalogue number
GC31701
Brand
GLPBIO
Computed properties PubChem CID 6603792 · XLogP 4.6 · TPSA 66 Ų · H-bond donors 1
XLogP
4.6
TPSA
66 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
28

SMILES C1CCC(C1)N2C=C(C3=C(N=CN=C32)N)C4=CC=C(C=C4)OC5=CC=CC=C5

Computed descriptors from PubChem (CID 6603792), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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