GC39636
PF-06952229
Also known as 4-[[2-(5-chloro-2-fluorophenyl)-5-propan-2-yl-4-pyridinyl]amino]-N-(1,3-dihydroxypropan-2-yl)pyridine-3-carboxamide
PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor· PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction·?PF-06952229 is a promising antineoplastic?agent for the study solid tumors, especifically metastatic breast cancer
ChemicalCAS1801333-55-0MW458.91FormulaC23H24ClFN4O3
- CAS number
- 1801333-55-0
- Molecular weight
- 458.91
- Formula
- C23H24ClFN4O3
- Solubility
- Soluble in DMSO
- InChIKey
- IPBLCOKXDQHSQW-UHFFFAOYSA-N
- Catalogue number
- GC39636
- Brand
- GLPBIO
Computed properties PubChem CID 118211239 · XLogP 3.4 · TPSA 107 Ų · H-bond donors 4
- XLogP
- 3.4
- TPSA
- 107 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Rotatable bonds
- 8
- Heavy atoms
- 32
SMILES CC(C)C1=CN=C(C=C1NC2=C(C=NC=C2)C(=O)NC(CO)CO)C3=C(C=CC(=C3)Cl)F
Computed descriptors from PubChem (CID 118211239), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il