Loading...
Chemical structure of DB1976

GC39627

DB1976

Also known as 2-[5-(6-carbamimidoyl-1H-benzimidazol-2-yl)selenophen-2-yl]-3H-benzimidazole-5-carboximidamide

DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU·1 inhibitor· DB1976 potently inhibits PU·1 binding (IC50 of 10 nM) and strongly inhibits the PU·1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro· DB1976 has apoptosis-inducing effect

ChemicalCAS1557397-51-9MW447.35FormulaC20H16N8Se
CAS number
1557397-51-9
Molecular weight
447.35
Formula
C20H16N8Se
Solubility
Soluble in DMSO
InChIKey
NXECULIQZLOKFU-UHFFFAOYSA-N
Catalogue number
GC39627
Brand
GLPBIO
Computed properties PubChem CID 141655595 · TPSA 157 Ų · H-bond donors 6 · H-bond acceptors 4
TPSA
157 Ų
H-bond donors
6
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
29

SMILES C1=CC2=C(C=C1C(=N)N)NC(=N2)C3=CC=C([Se]3)C4=NC5=C(N4)C=C(C=C5)C(=N)N

Computed descriptors from PubChem (CID 141655595), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.