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Chemical structure of DB2313

GC62222

DB2313

Also known as 2-[4-[[2-fluoro-3-[[4-[6-(N'-propan-2-ylcarbamimidoyl)-1H-benzimidazol-2-yl]phenoxy]methyl]phenyl]methoxy]phenyl]-N'-propan-2-yl-3H-benzimidazole-5-carboximidamide

DB2313 is a potent transcription factor PU·1 inhibitor with an apoptosis of 14 nM· DB2313 disrupts the interaction of PU·1 with target gene promoters· DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects

ChemicalCAS2170606-74-1MW708.83FormulaC42H41FN8O2
CAS number
2170606-74-1
Molecular weight
708.83
Formula
C42H41FN8O2
Solubility
DMSO ： 3·7 mg/mL (5·22 mM; ultrasonic and warming and heat to 70°C)
InChIKey
NUVPJXUYFGWDGB-UHFFFAOYSA-N
Catalogue number
GC62222
Brand
GLPBIO
Computed properties PubChem CID 138556040 · XLogP 6.9 · TPSA 153 Ų · H-bond donors 4
XLogP
6.9
TPSA
153 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
12
Heavy atoms
53

SMILES CC(C)N=C(C1=CC2=C(C=C1)N=C(N2)C3=CC=C(C=C3)OCC4=C(C(=CC=C4)COC5=CC=C(C=C5)C6=NC7=C(N6)C=C(C=C7)C(=NC(C)C)N)F)N

Computed descriptors from PubChem (CID 138556040), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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