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Chemical structure of GSK-3484862

GC39491

GSK-3484862

Also known as (2R)-2-[[3,5-dicyano-6-(dimethylamino)-4-ethyl-2-pyridinyl]sulfanyl]-2-phenylacetamide

GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1)· GSK-3484862 induces DNA hypomethylation to against cancer· GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity

ChemicalCAS2170136-65-7MW365.45FormulaC19H19N5OS
CAS number
2170136-65-7
Molecular weight
365.45
Formula
C19H19N5OS
Solubility
Soluble in DMSO
InChIKey
KIEQQZZDWUNUQK-MRXNPFEDSA-N
Catalogue number
GC39491
Brand
GLPBIO
Computed properties PubChem CID 132233666 · XLogP 3 · TPSA 132 Ų · H-bond donors 1
XLogP
3
TPSA
132 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
26

SMILES CCC1=C(C(=NC(=C1C#N)S[C@H](C2=CC=CC=C2)C(=O)N)N(C)C)C#N

Computed descriptors from PubChem (CID 132233666), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.