GC39488
GFB-8438
Also known as 5-chloro-4-[3-oxo-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1H-pyridazin-6-one
GFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0·18 and 0·29 μM of hTRPC5 and hTRPC4, respectively
ChemicalCAS2304549-73-1MW386.76FormulaC16H14ClF3N4O2
- CAS number
- 2304549-73-1
- Molecular weight
- 386.76
- Formula
- C16H14ClF3N4O2
- Solubility
- DMSO： 83·33 mg/mL (215·46 mM)
- InChIKey
- MITRKIWBJVJRAM-UHFFFAOYSA-N
- Catalogue number
- GC39488
- Brand
- GLPBIO
Computed properties PubChem CID 138471783 · XLogP 2.1 · TPSA 65 Ų · H-bond donors 1
- XLogP
- 2.1
- TPSA
- 65 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 3
- Heavy atoms
- 26
SMILES C1CN(C(=O)CN1C2=C(C(=O)NN=C2)Cl)CC3=CC=CC=C3C(F)(F)F
Computed descriptors from PubChem (CID 138471783), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il