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Chemical structure of GF 109203X (Bisindolylmaleimide I)

GC15431

GF 109203X (Bisindolylmaleimide I)

Also known as 3-[1-[3-(dimethylamino)propyl]indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione

GF 109203X is a selective inhibitor of protein kinase C, selective for the α and β1 isoforms with IC50 values of 0·0084, 0·0180, 0·210, 0·132, and 5·8μM for α, β1, δ, ε and ζ isoforms of protein kinase C respectively

ChemicalCAS133052-90-1MW412.49FormulaC25H24N4O2
CAS number
133052-90-1
Molecular weight
412.49
Formula
C25H24N4O2
Solubility
≥ 20·6mg/mL in DMSO
InChIKey
QMGUOJYZJKLOLH-UHFFFAOYSA-N
Catalogue number
GC15431
Brand
GLPBIO
Computed properties PubChem CID 2396 · XLogP 3.1 · TPSA 70.1 Ų · H-bond donors 2
XLogP
3.1
TPSA
70.1 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
31

SMILES CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54

Computed descriptors from PubChem (CID 2396), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.