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Chemical structure of YKL-06-062

GC39195

YKL-06-062

Also known as 1-cyclohexyl-3-(2,6-dimethylphenyl)-7-[4-(4-methylpiperazin-1-yl)anilino]-4H-pyrimido[4,5-d]pyrimidin-2-one

YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2·12 nM/1·40 nM/2·86 nM, respectively

ChemicalCAS2172617-16-0MW525.69FormulaC31H39N7O
CAS number
2172617-16-0
Molecular weight
525.69
Formula
C31H39N7O
Solubility
DMSO ： 25 mg/mL (47·56 mM; Need ultrasonic)
InChIKey
GFXPGVPPWWPDPV-UHFFFAOYSA-N
Catalogue number
GC39195
Brand
GLPBIO
Computed properties PubChem CID 139600310 · XLogP 5.4 · TPSA 67.8 Ų · H-bond donors 1
XLogP
5.4
TPSA
67.8 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
39

SMILES CC1=C(C(=CC=C1)C)N2CC3=CN=C(N=C3N(C2=O)C4CCCCC4)NC5=CC=C(C=C5)N6CCN(CC6)C

Computed descriptors from PubChem (CID 139600310), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.