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Chemical structure of GKA50

GC38784

GKA50

Also known as 6-[[3-[(2S)-1-methoxypropan-2-yl]oxy-5-[(2S)-1-phenylpropan-2-yl]oxybenzoyl]amino]pyridine-3-carboxylic acid

GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose)

ChemicalCAS851884-87-2MW464.51FormulaC26H28N2O6
CAS number
851884-87-2
Molecular weight
464.51
Formula
C26H28N2O6
Solubility
DMSO : 46 mg/mL (99·03 mM; Need ultrasonic and warming)
InChIKey
OCBMECSFDVUYQN-ROUUACIJSA-N
Catalogue number
GC38784
Brand
GLPBIO
Computed properties PubChem CID 11340230 · XLogP 4.2 · TPSA 107 Ų · H-bond donors 2
XLogP
4.2
TPSA
107 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
11
Heavy atoms
34

SMILES C[C@@H](CC1=CC=CC=C1)OC2=CC(=CC(=C2)C(=O)NC3=NC=C(C=C3)C(=O)O)O[C@@H](C)COC

Computed descriptors from PubChem (CID 11340230), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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