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Chemical structure of P62-mediated mitophagy inducer

GC38562

P62-mediated mitophagy inducer

Also known as 1-(3-iodophenyl)-4-(3-nitrophenyl)triazole

P62-mediated mitophagy inducer is a mitophagy regulator which activates mitophagy without recruiting Parkin or collapsing ΔΨm and retains activity in cells devoid of a fully functional PINK1/Parkin pathway

ChemicalCAS1809031-84-2MW392.15FormulaC14H9IN4O2
CAS number
1809031-84-2
Molecular weight
392.15
Formula
C14H9IN4O2
Solubility
DMSO: 1 mg/mL (2·55 mM; ultrasonic and adjust pH to 3 with 0·1 M HCL)
InChIKey
LSVWEYNSNZJEGB-UHFFFAOYSA-N
Catalogue number
GC38562
Brand
GLPBIO
Computed properties PubChem CID 122190591 · XLogP 3.5 · TPSA 76.5 Ų · H-bond donors 0
XLogP
3.5
TPSA
76.5 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
21

SMILES C1=CC(=CC(=C1)[N+](=O)[O-])C2=CN(N=N2)C3=CC(=CC=C3)I

Computed descriptors from PubChem (CID 122190591), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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