Loading...
Chemical structure of P5(PEG24)-VC-PAB-exatecan

GC74021

P5(PEG24)-VC-PAB-exatecan

Also known as [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[[4-[[ethynyl-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]phosphoryl]amino]benzoyl]amino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]carbamate

P5(PEG24)-VC-PAB-exatecan is a camptothecin-based linker-payload platform based on the highly potent camptothecin derivative exatecan

ChemicalCAS2928571-43-9MW2105.31FormulaC100H151FN9O36P
CAS number
2928571-43-9
Molecular weight
2105.31
Formula
C100H151FN9O36P
Solubility
DMSO ： 100 mg/mL (47·50 mM; Need ultrasonic)
InChIKey
KZEPGSKCAWPFGG-HTZDUXJFSA-N
Catalogue number
GC74021
Brand
GLPBIO
Computed properties PubChem CID 172653110 · XLogP -1.1 · TPSA 531 Ų · H-bond donors 9
XLogP
-1.1
TPSA
531 Ų
H-bond donors
9
H-bond acceptors
39
Rotatable bonds
90
Heavy atoms
147

SMILES CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)OCC7=CC=C(C=C7)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)C8=CC=C(C=C8)NP(=O)(C#C)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)O

Computed descriptors from PubChem (CID 172653110), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.