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Chemical structure of PhiKan083 hydrochloride

GC36896

PhiKan083 hydrochloride

Also listed as PhiKan 083 hydrochloride

PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells

ChemicalCAS1050480-30-2MW274.79FormulaC16H19ClN2
CAS number
1050480-30-2
Molecular weight
274.79
Formula
C16H19ClN2
Solubility
Water: 2 mg/mL (7·28 mM and warming)
InChIKey
IXWVUPURFWFRNE-UHFFFAOYSA-N
Catalogue number
GC36896
Brand
GLPBIO
Computed properties PubChem CID 16255105 · TPSA 17 Ų · H-bond donors 2 · H-bond acceptors 1
TPSA
17 Ų
H-bond donors
2
H-bond acceptors
1
Rotatable bonds
3
Heavy atoms
19

SMILES CCN1C2=C(C=C(C=C2)CNC)C3=CC=CC=C31.Cl

Computed descriptors from PubChem (CID 16255105), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.