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Chemical structure of Philanthotoxin 74

GC12703

Philanthotoxin 74

Also known as N-[(2S)-1-[7-(4-aminobutylamino)heptylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]butanamide;dihydrochloride

Philanthotoxin 74 (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively

ChemicalCAS1227301-51-0MW507.54FormulaC24H42N4O3·2HCl
CAS number
1227301-51-0
Molecular weight
507.54
Formula
C24H42N4O3·2HCl
Solubility
DMSO: 100 mM,Water: 100 mM
InChIKey
HWTJQQMIKVJWLH-IKXQUJFKSA-N
Catalogue number
GC12703
Brand
GLPBIO
Computed properties PubChem CID 46213501 · TPSA 116 Ų · H-bond donors 7 · H-bond acceptors 5
TPSA
116 Ų
H-bond donors
7
H-bond acceptors
5
Rotatable bonds
18
Heavy atoms
33

SMILES CCCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)NCCCCCCCNCCCCN.Cl.Cl

Computed descriptors from PubChem (CID 46213501), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.