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Chemical structure of Phe-Met-Arg-Phe amide trifluoroacetate

GC33680

Phe-Met-Arg-Phe amide trifluoroacetate

Also known as (2S)-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-(diaminomethylideneamino)pentanamide;bis(2,2,2-trifluoroacetic acid)

Phe-Met-Arg-Phe amide trifluoroacetate is an activator of K+ current, with ED50 of 23 nM in the peptidergic caudodorsal neurons

ChemicalCAS159237-99-7MW826.81FormulaC33H44F6N8O8S
CAS number
159237-99-7
Molecular weight
826.81
Formula
C33H44F6N8O8S
Solubility
Water : ≥ 50 mg/mL (60·47 mM)
InChIKey
XVODPBULIXCTET-PAHQJZCISA-N
Catalogue number
GC33680
Brand
GLPBIO
Computed properties PubChem CID 131704523 · TPSA 321 Ų · H-bond donors 9 · H-bond acceptors 17
TPSA
321 Ų
H-bond donors
9
H-bond acceptors
17
Rotatable bonds
18
Heavy atoms
56

SMILES CSCC[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CC=CC=C2)N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 131704523), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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