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Chemical structure of ML367

GC36630

ML367

Also known as N-(3,4-difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity· ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation

ChemicalCAS381168-77-0MW334.32FormulaC19H12F2N4
CAS number
381168-77-0
Molecular weight
334.32
Formula
C19H12F2N4
Solubility
DMSO： ≥ 125 mg/mL (373·89 mM)
InChIKey
LBPYNNJXARHGAG-UHFFFAOYSA-N
Catalogue number
GC36630
Brand
GLPBIO
Computed properties PubChem CID 921541 · XLogP 4.2 · TPSA 50.7 Ų · H-bond donors 1
XLogP
4.2
TPSA
50.7 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
25

SMILES C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=NC=C3)NC4=CC(=C(C=C4)F)F

Computed descriptors from PubChem (CID 921541), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.