GC36625
MK-8033 hydrochloride
Also known as 1-[5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide;hydrochloride
MK-8033 hydrochloride is an orally active ATP competitive c-Met/Ron dual inhibitor (IC50s: 1 nM (c-Met),7 nM (Ron)), with preferential binding to the activated kinase conformation· MK-8033 hydrochloride can be used in the research of cancers, such as breast and bladder cancers, non-small cell lung cancers (NSCLCs)
ChemicalCAS1283000-43-0MW507.99FormulaC25H22ClN5O3S
- CAS number
- 1283000-43-0
- Molecular weight
- 507.99
- Formula
- C25H22ClN5O3S
- Solubility
- DMSO： ＜ 1 mg/mL (insoluble or slightly soluble)
- InChIKey
- BKIQDRGTLKPYCL-UHFFFAOYSA-N
- Catalogue number
- GC36625
- Brand
- GLPBIO
Computed properties PubChem CID 51030992 · TPSA 115 Ų · H-bond donors 2 · H-bond acceptors 7
- TPSA
- 115 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 35
SMILES CN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)N=C2.Cl
Computed descriptors from PubChem (CID 51030992), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il