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Chemical structure of LY2812223

GC36506

LY2812223

Also known as (1R,2S,4R,5R,6R)-2-amino-4-(1H-1,2,4-triazol-5-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid

LY2812223 is a highly potent, functionally selective mGlu2 receptor agonist with mGlu2 binding affinity for mGlu2 and mGlu3 (Ki=144 nM and 156 nM, respectively)

ChemicalCAS1311385-20-2MW284.29FormulaC10H12N4O4S
CAS number
1311385-20-2
Molecular weight
284.29
Formula
C10H12N4O4S
Solubility
Water： 50 mg/mL (175·88 mM); DMSO： 28·75 mg/mL (101·13 mM)
InChIKey
YSOWRGMLMZQSBX-AVUIYAGVSA-N
Catalogue number
GC36506
Brand
GLPBIO
Computed properties PubChem CID 53240406 · XLogP -2.9 · TPSA 167 Ų · H-bond donors 4
XLogP
-2.9
TPSA
167 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
19

SMILES C1[C@H]([C@H]2[C@@H]([C@H]2[C@@]1(C(=O)O)N)C(=O)O)SC3=NC=NN3

Computed descriptors from PubChem (CID 53240406), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.