Loading...
Chemical structure of Abemaciclib

GC11823

Abemaciclib

Also listed as LY2835219 free base

LY2835219 free base is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2nM and 10nM in cell-free assays, respectively

ChemicalCAS1231929-97-7MW506.59FormulaC27H32F2N8
CAS number
1231929-97-7
Molecular weight
506.59
Formula
C27H32F2N8
Solubility
≥ 4·83 mg/mL in DMSO with ultrasonic and warming, ≥ 6·34 mg/mL in EtOH with gentle warming
InChIKey
UZWDCWONPYILKI-UHFFFAOYSA-N
Catalogue number
GC11823
Brand
GLPBIO
Computed properties PubChem CID 46220502 · XLogP 3.8 · TPSA 75 Ų · H-bond donors 1
XLogP
3.8
TPSA
75 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
37

SMILES CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F

Computed descriptors from PubChem (CID 46220502), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.