Loading...
Chemical structure of H-1152 dihydrochloride

GC36208

H-1152 dihydrochloride

Also known as 4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline;dihydrochloride

H-1152 dihydrochloride is a membrane-permeable and selective ROCK inhibitor, with a Ki value of 1·6 nM, and an IC50 value of 12 nM for ROCK2

ChemicalCAS871543-07-6MW392.34FormulaC16H23Cl2N3O2S
CAS number
871543-07-6
Molecular weight
392.34
Formula
C16H23Cl2N3O2S
Solubility
DMSO： ≥ 32 mg/mL (81·56 mM)
InChIKey
BFOPDSJOLUQULZ-GXKRWWSZSA-N
Catalogue number
GC36208
Brand
GLPBIO
Computed properties PubChem CID 11560225 · TPSA 70.7 Ų · H-bond donors 3 · H-bond acceptors 5
TPSA
70.7 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
24

SMILES C[C@H]1CNCCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C.Cl.Cl

Computed descriptors from PubChem (CID 11560225), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.