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Chemical structure of H-1152

GC36207

H-1152

Also known as 4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline

H-1152 is a membrane-permeable and selective ROCK inhibitor, with a Ki value of 1·6 nM, and an IC50 value of 12 nM for ROCK2

ChemicalCAS451462-58-1MW319.42FormulaC16H21N3O2S
CAS number
451462-58-1
Molecular weight
319.42
Formula
C16H21N3O2S
Solubility
DMF： 15 mg/ml,DMSO： 12·5 mg/ml,Ethanol： 20 mg/ml,PBS (pH 7·2)： 10 mg/ml
InChIKey
AWDORCFLUJZUQS-ZDUSSCGKSA-N
Catalogue number
GC36207
Brand
GLPBIO
Computed properties PubChem CID 448043 · XLogP 1.7 · TPSA 70.7 Ų · H-bond donors 1
XLogP
1.7
TPSA
70.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
22

SMILES C[C@H]1CNCCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C

Computed descriptors from PubChem (CID 448043), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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