Loading...
Chemical structure of H-7 dihydrochloride

GC17923

H-7 dihydrochloride

Also known as 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline;dihydrochloride

H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor· At 100 μM, H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase)

ChemicalCAS108930-17-2MW364.29FormulaC14H17N3O2S·2HCl
CAS number
108930-17-2
Molecular weight
364.29
Formula
C14H17N3O2S·2HCl
Solubility
DMF： 2 mg/ml,DMSO： 10 mg/ml,Ethanol： 0·25 mg/ml,PBS (pH 7·2)： 10 mg/ml
InChIKey
OARGPFMFRLLKPF-UHFFFAOYSA-N
Catalogue number
GC17923
Brand
GLPBIO
Computed properties PubChem CID 73332 · TPSA 70.7 Ų · H-bond donors 3 · H-bond acceptors 5
TPSA
70.7 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
22

SMILES CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

Computed descriptors from PubChem (CID 73332), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.