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Chemical structure of GW284543

GC36199

GW284543

Also known as 6,7-dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine

GW284543 (UNC10225170) is a selective MEK5 inhibitor· GW284543 reduces pERK5, and decreases endogenous MYC protein

ChemicalCAS790186-68-4MW372.42FormulaC23H20N2O3
CAS number
790186-68-4
Molecular weight
372.42
Formula
C23H20N2O3
Solubility
DMSO: 125 mg/mL (335·64 mM)
InChIKey
LEEMRFWMAIVHQY-UHFFFAOYSA-N
Catalogue number
GC36199
Brand
GLPBIO
Computed properties PubChem CID 44531022 · XLogP 5.2 · TPSA 52.6 Ų · H-bond donors 1
XLogP
5.2
TPSA
52.6 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
28

SMILES COC1=CC2=C(C=CN=C2C=C1OC)NC3=CC(=CC=C3)OC4=CC=CC=C4

Computed descriptors from PubChem (CID 44531022), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.