Loading...
Chemical structure of GW2974

GC74863

GW2974

Also known as 4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine

GW2974 is a potent dual inhibitor of EGFR and HER2 with IC50 value of 0·007 μM and 0·016 μM, respectively

ChemicalCAS202272-68-2MW395.46FormulaC23H21N7
CAS number
202272-68-2
Molecular weight
395.46
Formula
C23H21N7
Solubility
DMSO： 20 mg/mL (50·57 mM; Need ultrasonic and warming)
InChIKey
DYYZXRCFCVDSKD-UHFFFAOYSA-N
Catalogue number
GC74863
Brand
GLPBIO
Computed properties PubChem CID 6603857 · XLogP 4 · TPSA 71.8 Ų · H-bond donors 1
XLogP
4
TPSA
71.8 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
30

SMILES CN(C)C1=NC=C2C(=C1)C(=NC=N2)NC3=CC4=C(C=C3)N(N=C4)CC5=CC=CC=C5

Computed descriptors from PubChem (CID 6603857), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.