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Chemical structure of GW274150

GC31673

GW274150

Also known as (2S)-2-amino-4-[2-(1-aminoethylideneamino)ethylsulfanyl]butanoic acid

GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2·19 μM; Kd=40 nM) and rat iNOS (ED50=1·15 μM)

ChemicalCAS210354-22-6MW219.3FormulaC8H17N3O2S
CAS number
210354-22-6
Molecular weight
219.3
Formula
C8H17N3O2S
Solubility
Water : ≥ 62 mg/mL (282·72 mM)
InChIKey
MOLOJNHYNHBPCW-ZETCQYMHSA-N
Catalogue number
GC31673
Brand
GLPBIO
Computed properties PubChem CID 9797017 · XLogP -3.3 · TPSA 127 Ų · H-bond donors 3
XLogP
-3.3
TPSA
127 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
14

SMILES CC(=NCCSCC[C@@H](C(=O)O)N)N

Computed descriptors from PubChem (CID 9797017), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.