GC36193
GSK-3β inhibitor 1
Also known as (3Z)-3-(pyridin-2-ylmethylidene)-1H-indol-2-one
GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4·9 nM
ChemicalCAS187325-53-7MW222.24FormulaC14H10N2O
- CAS number
- 187325-53-7
- Molecular weight
- 222.24
- Formula
- C14H10N2O
- Solubility
- DMSO ： 33·33 mg/mL (149·97 mM; Need ultrasonic)
- InChIKey
- YKQONSWBHGBDSB-XFXZXTDPSA-N
- Catalogue number
- GC36193
- Brand
- GLPBIO
Computed properties PubChem CID 5796182 · XLogP 1.9 · TPSA 42 Ų · H-bond donors 1
- XLogP
- 1.9
- TPSA
- 42 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 17
SMILES C1=CC=C2C(=C1)/C(=C/C3=CC=CC=N3)/C(=O)N2
Computed descriptors from PubChem (CID 5796182), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il