GC35628
Cdc7-IN-1
Also known as ethyl 2-(2-chloroanilino)-4-hydroxy-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]furan-3-carboxylate
Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0·6 nM at 1 mM ATP and with slow off-rate characteristics· Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death
ChemicalCAS1402055-25-7MW409.82FormulaC21H16ClN3O4
- CAS number
- 1402055-25-7
- Molecular weight
- 409.82
- Formula
- C21H16ClN3O4
- Solubility
- DMSO： 5·2 mg/mL (12·69 mM)
- InChIKey
- MNEODYFHQBZJNQ-ZRDIBKRKSA-N
- Catalogue number
- GC35628
- Brand
- GLPBIO
Computed properties PubChem CID 136230445 · XLogP 4.4 · TPSA 97 Ų · H-bond donors 2
- XLogP
- 4.4
- TPSA
- 97 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 29
SMILES CCOC(=O)C1=C(OC(=C1O)/C=C/2\C=NC3=C2C=CC=N3)NC4=CC=CC=C4Cl
Computed descriptors from PubChem (CID 136230445), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il