Loading...
Chemical structure of BI 1015550

GC68758

BI 1015550

Also known as [1-[[(5R)-2-[4-(5-chloropyrimidin-2-yl)piperidin-1-yl]-5-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]cyclobutyl]methanol

BI 1015550 is an orally active PDE4B inhibitor with an IC50 value of 7·2 nM· It has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD)

ChemicalCAS1423719-30-5MW448.97FormulaC20H25ClN6O2S
CAS number
1423719-30-5
Molecular weight
448.97
Formula
C20H25ClN6O2S
Solubility
DMSO ： 10 mg/mL (22·27 mM; ultrasonic and warming and heat to 60°C)
InChIKey
UHYCLWAANUGUMN-SSEXGKCCSA-N
Catalogue number
GC68758
Brand
GLPBIO
Computed properties PubChem CID 166177189 · XLogP 1.3 · TPSA 123 Ų · H-bond donors 2
XLogP
1.3
TPSA
123 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
30

SMILES C1CC(C1)(CO)NC2=NC(=NC3=C2[S@](=O)CC3)N4CCC(CC4)C5=NC=C(C=N5)Cl

Computed descriptors from PubChem (CID 166177189), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.