GC35367
APG-115
APG-115 (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3·8 nM and 1 nM, respectively· APG-115 blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner
ChemicalCAS1818393-16-6MW642.59FormulaC34H38Cl2FN3O4
- CAS number
- 1818393-16-6
- Molecular weight
- 642.59
- Formula
- C34H38Cl2FN3O4
- Solubility
- Soluble in DMSO
- InChIKey
- YJCZPJQGFSSFOL-MNZPCBJKSA-N
- Catalogue number
- GC35367
- Brand
- GLPBIO
Computed properties PubChem CID 91972012 · XLogP 3.6 · TPSA 98.7 Ų · H-bond donors 3
- XLogP
- 3.6
- TPSA
- 98.7 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Rotatable bonds
- 5
- Heavy atoms
- 44
SMILES CCN1[C@H]([C@@H]([C@]2(C13CCCCC3)C4=C(C=C(C=C4)Cl)NC2=O)C5=C(C(=CC=C5)Cl)F)C(=O)NC67CCC(CC6)(CC7)C(=O)O
Computed descriptors from PubChem (CID 91972012), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il