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Chemical structure of SRI 31215 TFA

GC34811

SRI 31215 TFA

Also known as 3-[3-[(1-benzylpiperidin-4-yl)methyl]-5-methyl-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide;2,2,2-trifluoroacetic acid

SRI 31215 (TFA) is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation)· SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC50 values of 0·69 μM, 0·65 μM and 0·30 μM, respectively· SRI 31215 can be used for the research of cancer

ChemicalCAS1832686-44-8MW533.59FormulaC27H34F3N5O3
CAS number
1832686-44-8
Molecular weight
533.59
Formula
C27H34F3N5O3
Solubility
Soluble in DMSO
InChIKey
QJFJKJLPPLYFJA-UHFFFAOYSA-N
Catalogue number
GC34811
Brand
GLPBIO
Computed properties PubChem CID 102004307 · TPSA 114 Ų · H-bond donors 3 · H-bond acceptors 8
TPSA
114 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
38

SMILES CC1CN(C(=O)N(C1)C2=CC=CC(=C2)C(=N)N)CC3CCN(CC3)CC4=CC=CC=C4.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 102004307), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.