GC34372
IL-17A antagonist 1
Also known as N-[(2S)-1-[4-[2-[[2-[1-[2-(dimethylamino)-2-oxoethyl]cyclopentyl]acetyl]amino]ethyl]anilino]-3-(2-fluorophenyl)-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide
IL-17A antagonist 1 (compound 1) is an IL-17A antagonist, with a Kd of 0·66 μM and an IC50 of 1·14 μM
ChemicalCAS2205034-18-8MW604.71FormulaC33H41FN6O4
- CAS number
- 2205034-18-8
- Molecular weight
- 604.71
- Formula
- C33H41FN6O4
- Solubility
- DMSO ： 41·67 mg/mL (68·91 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- VWRXSIAIHJZTCV-MHZLTWQESA-N
- Catalogue number
- GC34372
- Brand
- GLPBIO
Computed properties PubChem CID 121499148 · XLogP 3.8 · TPSA 125 Ų · H-bond donors 3
- XLogP
- 3.8
- TPSA
- 125 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Rotatable bonds
- 13
- Heavy atoms
- 44
SMILES CN1C(=CC=N1)C(=O)N[C@@H](CC2=CC=CC=C2F)C(=O)NC3=CC=C(C=C3)CCNC(=O)CC4(CCCC4)CC(=O)N(C)C
Computed descriptors from PubChem (CID 121499148), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il