GC62659
IL-17A inhibitor 1
Also known as N-[(S)-(4,4-difluorocyclohexyl)-[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)imidazolidin-1-yl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl-1,2,5-oxadiazole-3-carboxamide
IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of ＜9·45 nM and 9·3 nM in alphalisa assay and HT-29 cells
ChemicalCAS2452464-73-0MW586.51FormulaC24H27F5N8O4
- CAS number
- 2452464-73-0
- Molecular weight
- 586.51
- Formula
- C24H27F5N8O4
- Solubility
- DMSO ： 250 mg/mL (426·25 mM; Need ultrasonic)
- InChIKey
- MVWVCLAORBNXSD-UWVAXJGDSA-N
- Catalogue number
- GC62659
- Brand
- GLPBIO
Computed properties PubChem CID 154642729 · XLogP 1.8 · TPSA 140 Ų · H-bond donors 2
- XLogP
- 1.8
- TPSA
- 140 Ų
- H-bond donors
- 2
- H-bond acceptors
- 13
- Rotatable bonds
- 8
- Heavy atoms
- 41
SMILES CC1=NON=C1C(=O)N[C@@H](C2CCC(CC2)(F)F)C3=CN4C(=N3)C=C(C=N4)[C@@H](COC)N5C[C@H](NC5=O)C(F)(F)F
Computed descriptors from PubChem (CID 154642729), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il