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Chemical structure of AZ7550 hydrochloride

GC34287

AZ7550 hydrochloride

Also known as N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide;hydrochloride

AZ7550 hydrochloride is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1·6 μM

ChemicalCAS2309762-40-9MW522.04FormulaC27H32ClN7O2
CAS number
2309762-40-9
Molecular weight
522.04
Formula
C27H32ClN7O2
Solubility
DMSO : 1·88 mg/mL (3·60 mM)
InChIKey
BHYPVGSNUFXTCM-UHFFFAOYSA-N
Catalogue number
GC34287
Brand
GLPBIO
Computed properties PubChem CID 132274051 · TPSA 96.3 Ų · H-bond donors 4 · H-bond acceptors 7
TPSA
96.3 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
37

SMILES CNCCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C)OC.Cl

Computed descriptors from PubChem (CID 132274051), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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