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Chemical structure of AZ82

GC18956

AZ82

Also known as 5-methyl-N-[(2R)-1-oxo-1-[[(3R)-pyrrolidin-3-yl]amino]-3-[6-[3-(trifluoromethoxy)phenyl]-3-pyridinyl]propan-2-yl]-4-propylthiophene-2-carboxamide

AZ82 is a small molecule inhibitor of KIFC1/HSET, a kinesin-14 family protein that is important for assembling bipolar spindles in cancer cells containing supernumerary centrosomes

ChemicalCAS1449578-65-7MW560.6FormulaC28H31F3N4O3S
CAS number
1449578-65-7
Molecular weight
560.6
Formula
C28H31F3N4O3S
Solubility
DMF： 20 mg/ml,DMSO： 20 mg/ml,Ethanol： 20 mg/ml,Ethanol：PBS (pH 7·2) (1：3)： 0·25 mg/ml
InChIKey
PMTLKNOARSHUJB-ZJSXRUAMSA-N
Catalogue number
GC18956
Brand
GLPBIO
Computed properties PubChem CID 91885438 · XLogP 5.8 · TPSA 121 Ų · H-bond donors 3
XLogP
5.8
TPSA
121 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
10
Heavy atoms
39

SMILES CCCC1=C(SC(=C1)C(=O)N[C@H](CC2=CN=C(C=C2)C3=CC(=CC=C3)OC(F)(F)F)C(=O)N[C@@H]4CCNC4)C

Computed descriptors from PubChem (CID 91885438), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.