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Chemical structure of AZ7550

GC33072

AZ7550

Also known as N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide

AZ7550 is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1·6 μM

ChemicalCAS1421373-99-0MW485.58FormulaC27H31N7O2
CAS number
1421373-99-0
Molecular weight
485.58
Formula
C27H31N7O2
Solubility
Soluble in DMSO
InChIKey
ZROCWKZRGJYPTG-UHFFFAOYSA-N
Catalogue number
GC33072
Brand
GLPBIO
Computed properties PubChem CID 71496459 · XLogP 3.3 · TPSA 96.3 Ų · H-bond donors 3
XLogP
3.3
TPSA
96.3 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
36

SMILES CNCCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C)OC

Computed descriptors from PubChem (CID 71496459), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.