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Chemical structure of CM-579

GC33320

CM-579

Also known as 6-methoxy-2-(5-methylfuran-2-yl)-N-[(1-methylpiperidin-4-yl)methyl]-7-(3-pyrrolidin-1-ylpropoxy)quinolin-4-amine

CM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively· Has potent in vitro cellular activity in a wide range of cancer cells

ChemicalCAS1846570-40-8MW492.65FormulaC29H40N4O3
CAS number
1846570-40-8
Molecular weight
492.65
Formula
C29H40N4O3
Solubility
Soluble in DMSO
InChIKey
VMMRDFLDWHFNOX-UHFFFAOYSA-N
Catalogue number
GC33320
Brand
GLPBIO
Computed properties PubChem CID 118613729 · XLogP 4.9 · TPSA 63 Ų · H-bond donors 1
XLogP
4.9
TPSA
63 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
36

SMILES CC1=CC=C(O1)C2=NC3=CC(=C(C=C3C(=C2)NCC4CCN(CC4)C)OC)OCCCN5CCCC5

Computed descriptors from PubChem (CID 118613729), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.