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Chemical structure of CM-675

GC65426

CM-675

Also known as N-(2-aminophenyl)-4-[[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)phenyl]methyl]benzamide

CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively

ChemicalCAS1872466-47-1MW536.62FormulaC31H32N6O3
CAS number
1872466-47-1
Molecular weight
536.62
Formula
C31H32N6O3
Solubility
DMSO ： 25 mg/mL (46·59 mM; ultrasonic and warming and heat to 60°C)
InChIKey
IUKGCTNFPZAWGC-UHFFFAOYSA-N
Catalogue number
GC65426
Brand
GLPBIO
Computed properties PubChem CID 136955224 · XLogP 4.6 · TPSA 124 Ų · H-bond donors 3
XLogP
4.6
TPSA
124 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
40

SMILES CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)CC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5N)OCC)C

Computed descriptors from PubChem (CID 136955224), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.