GC12367
CM-272
Also known as 6-methoxy-2-(5-methylfuran-2-yl)-N-(1-methylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinolin-4-amine
CM-272 is a first-in-class reversible dual inhibitor against G9a and DNMTs with IC50 values of 8 nM and 382 nM, respectively [1]
ChemicalCAS1846570-31-7MW478.63FormulaC28H38N4O3
- CAS number
- 1846570-31-7
- Molecular weight
- 478.63
- Formula
- C28H38N4O3
- Solubility
- DMF： 30 mg/ml,DMSO： 30 mg/ml,Ethanol： 30 mg/ml,Ethanol：PBS (pH 7·2) (1：6)： 0·15 mg/ml
- InChIKey
- RLQLKZTYUYIWDB-UHFFFAOYSA-N
- Catalogue number
- GC12367
- Brand
- GLPBIO
Computed properties PubChem CID 118607432 · XLogP 4.8 · TPSA 63 Ų · H-bond donors 1
- XLogP
- 4.8
- TPSA
- 63 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 9
- Heavy atoms
- 35
SMILES CC1=CC=C(O1)C2=NC3=CC(=C(C=C3C(=C2)NC4CCN(CC4)C)OC)OCCCN5CCCC5
Computed descriptors from PubChem (CID 118607432), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il