Loading...
Chemical structure of HDAC6-IN-1

GC33317

HDAC6-IN-1

Also known as N-hydroxy-4-[2-methoxy-5-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]butanamide

HDAC6-IN-1 is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively

ChemicalCAS1815580-06-3MW396.44FormulaC21H24N4O4
CAS number
1815580-06-3
Molecular weight
396.44
Formula
C21H24N4O4
Solubility
DMSO ： 32 mg/mL (80·72 mM)
InChIKey
FWXZZFONXWYSEF-UHFFFAOYSA-N
Catalogue number
GC33317
Brand
GLPBIO
Computed properties PubChem CID 122550211 · XLogP 3 · TPSA 96.8 Ų · H-bond donors 2
XLogP
3
TPSA
96.8 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
29

SMILES CC1=NC2=CC=CC=C2C(=N1)N(C)C3=CC(=C(C=C3)OC)OCCCC(=O)NO

Computed descriptors from PubChem (CID 122550211), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.