GC33255
AZD4320
Also known as 4-[4-[(R)-[2-(4-chlorophenyl)phenyl]-hydroxymethyl]piperidin-1-yl]-N-[4-[[(2R)-4-[2-hydroxyethyl(methyl)amino]-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC50s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively
ChemicalCAS1357576-48-7MW945.53FormulaC45H48ClF3N4O7S3
- CAS number
- 1357576-48-7
- Molecular weight
- 945.53
- Formula
- C45H48ClF3N4O7S3
- Solubility
- DMSO： 125 mg/mL (132·20 mM)
- InChIKey
- UNEJSHNDABUZNY-UJNHCCGESA-N
- Catalogue number
- GC33255
- Brand
- GLPBIO
Computed properties PubChem CID 86661883 · XLogP 9.3 · TPSA 198 Ų · H-bond donors 4
- XLogP
- 9.3
- TPSA
- 198 Ų
- H-bond donors
- 4
- H-bond acceptors
- 14
- Rotatable bonds
- 18
- Heavy atoms
- 63
SMILES CN(CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCC(CC4)[C@H](C5=CC=CC=C5C6=CC=C(C=C6)Cl)O)S(=O)(=O)C(F)(F)F)CCO
Computed descriptors from PubChem (CID 86661883), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il