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Chemical structure of AZD4635

GC19049

AZD4635

Also known as 6-(2-chloro-6-methyl-4-pyridinyl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine

AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist· AZD4635 binds to human A2AR with a Ki of 1·7 nM and shows >30-fold selectivity over other adenosine receptors

ChemicalCAS1321514-06-0MW315.73FormulaC15H11ClFN5
CAS number
1321514-06-0
Molecular weight
315.73
Formula
C15H11ClFN5
Solubility
DMSO ： ≥ 83·3 mg/mL (263·83 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
NCWQLHHDGDXIJN-UHFFFAOYSA-N
Catalogue number
GC19049
Brand
GLPBIO
Computed properties PubChem CID 86676119 · XLogP 2.6 · TPSA 77.6 Ų · H-bond donors 1
XLogP
2.6
TPSA
77.6 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
22

SMILES CC1=CC(=CC(=N1)Cl)C2=C(N=C(N=N2)N)C3=CC=C(C=C3)F

Computed descriptors from PubChem (CID 86676119), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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