GC33172
BGB-102 (JNJ-26483327)
Also known as 5-bromo-18-methoxy-10-methyl-16-oxa-2,10,21,23-tetrazatetracyclo[15.6.2.03,8.020,24]pentacosa-1(23),3(8),4,6,17,19,21,24-octaene
BGB-102 (JNJ-26483327) is a potent multi-kinase inhibitor against EGFR, HER2, and HER4 with IC50s of 9·6 nM, 18 nM and 40·3 nM, respectively
ChemicalCAS807640-87-5MW457.36FormulaC22H25BrN4O2
- CAS number
- 807640-87-5
- Molecular weight
- 457.36
- Formula
- C22H25BrN4O2
- Solubility
- Soluble in DMSO
- InChIKey
- JXDYOSVKVSQGJM-UHFFFAOYSA-N
- Catalogue number
- GC33172
- Brand
- GLPBIO
Computed properties PubChem CID 11952856 · XLogP 4.7 · TPSA 59.5 Ų · H-bond donors 1
- XLogP
- 4.7
- TPSA
- 59.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Rotatable bonds
- 1
- Heavy atoms
- 29
SMILES CN1CCCCCOC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C1)C=CC(=C4)Br)OC
Computed descriptors from PubChem (CID 11952856), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il