Loading...
Chemical structure of Ilginatinib hydrochloride

GC33037

Ilginatinib hydrochloride

Also listed as Ilginatinib hydrochloride (NS-018 hydrochloride)

Ilginatinib hydrochloride (NS-018 hydrochloride) (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0·72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM)

ChemicalCAS1239358-85-0MW425.89FormulaC21H21ClFN7
CAS number
1239358-85-0
Molecular weight
425.89
Formula
C21H21ClFN7
Solubility
DMSO ： ≥ 35 mg/mL (82·18 mM)
InChIKey
XFNVGPXGVAXXSH-UQKRIMTDSA-N
Catalogue number
GC33037
Brand
GLPBIO
Computed properties PubChem CID 89571724 · TPSA 80.6 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
80.6 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
30

SMILES C[C@@H](C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C.Cl

Computed descriptors from PubChem (CID 89571724), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.