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Chemical structure of NS-018 maleate

GC33018

NS-018 maleate

Also listed as Ilginatinib maleate (NS-018 (maleate))

Ilginatinib maleate (NS-018 (maleate)) (NS-018 maleate) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0·72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM)

ChemicalCAS1354799-87-3MW505.5FormulaC25H24FN7O4
CAS number
1354799-87-3
Molecular weight
505.5
Formula
C25H24FN7O4
Solubility
DMSO ： ≥ 30 mg/mL (59·35 mM)
InChIKey
OVAGJAAQMBYZDS-FXSDFHGDSA-N
Catalogue number
GC33018
Brand
GLPBIO
Computed properties PubChem CID 56599590 · TPSA 155 Ų · H-bond donors 4 · H-bond acceptors 11
TPSA
155 Ų
H-bond donors
4
H-bond acceptors
11
Rotatable bonds
8
Heavy atoms
37

SMILES C[C@@H](C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C.C(=C\C(=O)O)\C(=O)O

Computed descriptors from PubChem (CID 56599590), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.