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Chemical structure of Naquotinib Mesylate

GC32836

Naquotinib Mesylate

Also listed as Naquotinib mesylate (ASP8273)

Naquotinib mesylate (ASP8273) (ASP8273 mesylate) is an orally available, mutant-selective and irreversible EGFR inhibitor; with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR

ChemicalCAS1448237-05-5MW658.81FormulaC31H46N8O6S
CAS number
1448237-05-5
Molecular weight
658.81
Formula
C31H46N8O6S
Solubility
DMSO : 12·5 mg/mL (18·97 mM)
InChIKey
ALDUQYYVQWGTMR-GJFSDDNBSA-N
Catalogue number
GC32836
Brand
GLPBIO
Computed properties PubChem CID 92135932 · TPSA 183 Ų · H-bond donors 3 · H-bond acceptors 12
TPSA
183 Ų
H-bond donors
3
H-bond acceptors
12
Rotatable bonds
9
Heavy atoms
46

SMILES CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)O[C@@H]5CCN(C5)C(=O)C=C.CS(=O)(=O)O

Computed descriptors from PubChem (CID 92135932), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.