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Chemical structure of Naquotinib

GC33022

Naquotinib

Also listed as Naquotinib (ASP8273)

Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR

ChemicalCAS1448232-80-1MW562.71FormulaC30H42N8O3
CAS number
1448232-80-1
Molecular weight
562.71
Formula
C30H42N8O3
Solubility
DMF： 30mg/ml,DMSO： 2 mg/ml,Ethanol： 30mg/ml
InChIKey
QKDCLUARMDUUKN-XMMPIXPASA-N
Catalogue number
GC33022
Brand
GLPBIO
Computed properties PubChem CID 71667668 · XLogP 3.4 · TPSA 120 Ų · H-bond donors 2
XLogP
3.4
TPSA
120 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
41

SMILES CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)O[C@@H]5CCN(C5)C(=O)C=C

Computed descriptors from PubChem (CID 71667668), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.