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Chemical structure of EGF816 mesylate

GC36699

EGF816 mesylate

Also listed as Nazartinib mesylate

Nazartinib mesylate (EGF816 mesylate) is a novel, covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0·222 min?1 on EGFR(L858R/790M) mutant, respectively

ChemicalCAS1508250-72-3MW591.12FormulaC27H35ClN6O5S
CAS number
1508250-72-3
Molecular weight
591.12
Formula
C27H35ClN6O5S
Solubility
Soluble in DMSO
InChIKey
BJRYTAMUVASSBY-ZJULCNDBSA-N
Catalogue number
GC36699
Brand
GLPBIO
Computed properties PubChem CID 91809207 · TPSA 146 Ų · H-bond donors 2 · H-bond acceptors 8
TPSA
146 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
40

SMILES CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2[C@@H]4CCCCN(C4)C(=O)/C=C/CN(C)C)C(=CC=C3)Cl.CS(=O)(=O)O

Computed descriptors from PubChem (CID 91809207), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.