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Chemical structure of AD80

GC32797

AD80

Also known as 1-[4-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea

AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity

ChemicalCAS1384071-99-1MW473.43FormulaC22H19F4N7O
CAS number
1384071-99-1
Molecular weight
473.43
Formula
C22H19F4N7O
Solubility
DMSO : ≥ 150 mg/mL (316·84 mM)
InChIKey
CYORWDWRQMVGHN-UHFFFAOYSA-N
Catalogue number
GC32797
Brand
GLPBIO
Computed properties PubChem CID 71578106 · XLogP 3.7 · TPSA 111 Ų · H-bond donors 3
XLogP
3.7
TPSA
111 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
4
Heavy atoms
34

SMILES CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)N

Computed descriptors from PubChem (CID 71578106), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.