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Chemical structure of AD57 (hydrochloride)

GC16362

AD57 (hydrochloride)

Also known as 1-[4-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea;hydrochloride

polypharmacological cancer therapeutic that inhibits RET

ChemicalCAS2320261-72-9MW491.9FormulaC22H20F3N7O • HCl
CAS number
2320261-72-9
Molecular weight
491.9
Formula
C22H20F3N7O • HCl
Solubility
≤5mg/ml in ethanol;10mg/ml in DMSO;14mg/ml in dimethyl formamide
InChIKey
DUBKXOIZTZQJIW-UHFFFAOYSA-N
Catalogue number
GC16362
Brand
GLPBIO
Computed properties PubChem CID 132285143 · TPSA 111 Ų · H-bond donors 4 · H-bond acceptors 8
TPSA
111 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
34

SMILES CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)NC(=O)NC4=CC=CC(=C4)C(F)(F)F)N.Cl

Computed descriptors from PubChem (CID 132285143), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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